Our Research
Influenza A virus (IAV) represents a major global health burden. The virus is able to escape seasonal immunity requiring yearly vaccination and the threat of novel pandemics loom. Therefore, continued understanding of the host-pathogen interactions and protective immune responses are critical for the development of therapeutic interventions and protective vaccines. We aim to address fundamental questions in virology and viral immunology that have been difficult to dissect using conventional approaches. We generate novel recombinant viruses, virus host model systems, and animal models to probe the antiviral responses.
We are also interested in how viruses evolve in the face of antiviral immune responses and how viruses make jumps into new species. To study this we use a newly developed model system to track viruses within both the reservoir and host, where we can perturb key components of the immune system in the host.
Join Us
We are looking for new researchers, technicians, postdoctoral fellows, and other dedicated researchers to join our lab. Email inquires to: langlois@umn.edu.